Intracellular Ca2+ release sparks atrial pacemaker activity.
نویسندگان
چکیده
Electrical excitation of the mammalian heart originates from specialized pacemaker cells in the right atrium. Pacemaker activity depends on multiple ion channels and transport mechanisms that reside primarily within the plasma membrane. However, recent evidence indicates that intracellular Ca2+ release from the sarcoplasmic reticulum also contributes importantly to atrial pacemaker function.
منابع مشابه
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عنوان ژورنال:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
دوره 16 شماره
صفحات -
تاریخ انتشار 2001